point to note

in the last piece of work:
1) thanks to KT, it should be icosahedral head. it is ICO.

2)

3)know that virus can take its envelope from any fellow of the endomembrane system. It doesn't have to be plasma memb all the time!!
But when describing in general, for the syllabus, we will stick to plasma memb as the one best studied.

Eg. Herpes Virus - the nucleocapsid is assembled in the nucleus. The capsid buds off from the inner nuclear memb trasiently before fusing with the outer memb so that you get the nucleocapsid into the cytoplasm where it bud into golgi vesicles containing the viral proteins --> you get an enveloped virus (with membrane) enclosed by the membrane of the golgi vesicles. The virus is released by exocytosis/fusion with cell membrane.
It is pretty cool! If u are confused, you got to draw it out!

4) Hijack - what does it possibly entail? (this is not a comprehensive list)
a) destroy the host's genome --> no competition
b) modify host's RNA polymerase for its own use
c) produces its own viral polymerase and disable host polymerase
d) produce viral-related sigma factor and destroy host cell sigma factor (for phages) - linked to b) ; you are going to learn about sigma factor soon!


Ok!! That's all I have !!

Sorry folks but was away in Hongkong with my parents until Wed. Great trip but no need to do my travel blog since I fell sick on Day 1. But it was a great trip! :)

Cheers